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What (who) is MC1R - definition
MC1R
O MC1R ou receptor de melanocortina 1 é um receptor acoplado à proteína G, contendo sete hélices transmembranares. Sua ativação resulta na elevação dos níveis intracelulares de AMP cíclico (cAMP), numa cascata de transdução de sinal que termina com a estimulação da produção de eumelanina, um pigmento de cor marrom ou preta, que dá cor à pele e aos cabelos em seres humanos.
Examples of use of MC1R
1. The tests revealed the Neanderthals had a variant of MC1R which cuts melanin production.
2. They focused on the MC1R gene which helps skin make the "sunscreen" pigment melanin.
3. The mutation reduces the function of a gene known as MC1R.
4. They report in Friday‘s issue of the journal Science said that the mammoth DNA included the gene Mc1r.
5. Prof Mogil identified a mutant version of a gene called melanocortin–1 (Mc1r) that is linked to ginger hair and fair skin.